Safety and Efficacy of Oral Etrasimod in Adult Participants With Moderate-to-Severe Alopecia Areata

PHASE2CompletedINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

July 29, 2020

Primary Completion Date

June 7, 2023

Study Completion Date

June 7, 2023

Conditions
Alopecia Areata
Interventions
DRUG

Etrasimod

Etrasimod 2 mg tablet by mouth, once daily

DRUG

Etrasimod

Etrasimod 3 mg (1 mg and 2 mg tablets) by mouth, once daily

DRUG

Placebo

Etrasimod matching placebo tablet by mouth, once daily

Trial Locations (42)

10003

NYC Retina- Manhattan, New York

10012

Bobby Buka MD, PC, New York

14623

Rochester Ophthalmological Group, Rochester

Skin Search of Rochester, Inc., Rochester

15213

UPMC Department of Dermatology, Pittsburgh

UPMC Eye Center, Pittsburgh

20850

Lawrence J. Green, MD LLC, Rockville

24501

The Education & Research Foundation, Inc., Lynchburg

28405

WDC Cosmetic and Research, PLLC, Wilmington

30328

Advanced Medical Research PC, Sandy Springs

32117

Advanced Sleep & Respiratory Institute, PA, Daytona Beach

32174

International Eye Associates, Ormond Beach

Leavitt Medical Associates of Florida d/ba Ameriderm Research, Ormond Beach

33607

Advanced Clinical Research Institute, Tampa

37130

International Clinical Research - Tennessee LLC, Murfreesboro

46060

Physicians Research Group (Administrative Office Location), Noblesville

46250

Dawes Fretzin Clinical Research Group, LLC, Indianapolis

46260

Eye Surgeons of Indiana, Indianapolis

47905

Magnante Eye Care (Ophthalmological Assessments), Lafayette

47906

Physicians Research Group, West Lafayette

Randall Dermatology, PC, West Lafayette

48038

Michigan Center for Skin Care Research, Clinton Township

64506

MediSearch Clinical Trials, Saint Joseph

72022

Dermatology Trial Associates, Bryant

78213

Progressive Clinical Research, PA, San Antonio

85255

Investigate MD, Scottsdale

90717

Prospect Optometry, Lomita

Torrance Clinical Research Institute,Inc., Lomita

92024

California Dermatology & Clinical Research Institute, Encinitas

92697

University of California,Irvine, Irvine

92708

First OC Dermatology, Fountain Valley

97210

NW Dermatology Institute, Portland

99202

Dermatology Specialists of Spokane, Spokane

99204

PRINCIPLE RESEARCH SOLUTIONS (pulmonary function testing), Spokane

SPOKANE EYE CLINIC (OCT and optical exam, Spokane

06511

Yale Eye Center, New Haven

Yale Investigational Drug Services, New Haven

06519

Yale Center for Clinical Investigation, New Haven

Yale New Haven Hospital Department of Respiratory Care, New Haven

T2J 7E1

Dermatology Research Institute, Calgary

T5J 3S9

Laser Rejuvenation Clinics Edmonton D.T. Inc., Edmonton

H2X 2V1

Innovaderm Research, Montreal

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Arena is a wholly owned subsidiary of Pfizer

INDUSTRY

lead

Pfizer

INDUSTRY

NCT04556734 - Safety and Efficacy of Oral Etrasimod in Adult Participants With Moderate-to-Severe Alopecia Areata | Biotech Hunter | Biotech Hunter