20
Participants
Start Date
March 1, 2022
Primary Completion Date
May 31, 2022
Study Completion Date
June 30, 2022
Doxepin Topical
Four of the areas will be treated with doxepin for 1 hour and 30 minutes (with a patch to deposit 1.2 grams of cream). Each patch will be covered with Tegaderm I.V., an occlusive, adhesive dressing (3M), for at least 1½ hours
Papain
Papain will be applied by 1 SPT prick thought the skin
Histamine
Histamine will be applied by 1 SPT prick thought the skin
Cowhage
Cowhage spicules are 1-2 mm in length and have diameter of 1-3 µm at their tip. 30-35 spicules are gently rubbed into a 1 cm diameter skin area.
Aalborg University, Aalborg
Aalborg University
OTHER