The Effect of Systemic Antibiotics on Post-surgical Complications and Patient-centered Outcomes in Patients Undergoing Implant Surgery With Guided Bone Regeneration and Simultaneous Sinus Floor Elevation

PHASE4RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

December 29, 2022

Primary Completion Date

March 31, 2026

Study Completion Date

March 31, 2026

Conditions
Patients Undergoing Oral Implant Therapy
Interventions
DRUG

Amoxicillin

Preoperatively antibiotics of 2 g amoxicillin 1 hour prior to standard implant placement and sinus floor Elevation will be administered. An additional single dose of 500 mg of amoxicillin will be administered 8 hours after surgery and 500 mg thrice daily (8 hourly) on days 1 to 3 following implant placement and sinus floor elevation.

OTHER

Placebo

Preoperatively a placebo of 2 g will be administered. An additional single dose of 500 mg of placebo will be administered 8 hours after surgery and 500 mg thrice daily (8 hourly) on days 1 to 3 following implant placement and sinus floor elevation.

Trial Locations (1)

8010

RECRUITING

Medical University of Graz, University Hospital for Dentistry and Oral Health, Graz

All Listed Sponsors
lead

Medical University of Graz

OTHER