Bintrafusp Alfa Combination Therapy in Participants With Cervical Cancer (INTR@PID 046)

PHASE1CompletedINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

October 19, 2020

Primary Completion Date

June 15, 2022

Study Completion Date

June 30, 2022

Conditions
Cervical Cancer
Interventions
DRUG

M7824

Participants received bintrafusp alfa until confirmed disease progression, death, unacceptable toxicity and study withdrawal maximum of 2 years (at the discretion of the Investigator).

DRUG

Carboplatin

Carboplatin was administered intravenously as per standard of care.

DRUG

Paclitaxel

Paclitaxel was administered intravenously as per standard of care.

DRUG

Bevacizumab

Bevacizumab was administrated as indicated for standard of care.

DRUG

Cisplatin

Cisplatin was administered intravenously as per standard of care.

RADIATION

Radiotherapy

Participants received radiotherapy as per standard of care.

Trial Locations (13)

30912

Augusta University - formerly Georgia Regents University, Augusta

45206

University of Cincinnati Physicians Group, LLC - Pharmatech Oncology, Inc, Cincinnati

75390

UT Southwestern Medical Center, Dallas

89074

Comprehensive Cancer Centers of Nevada, Henderson

94305

Stanford Health Care Hospital & Clinics, Stanford

Unknown

National Cancer Center Hospital, Chūōku

Saitama Medical University International Medical Center, Hidaka-shi

Cancer Institute Hospital of JFCR, Kōtoku

Osaka International Cancer Institute, Osaka

Shizuoka Cancer Center, Sunto-gun

Hospital Clinic i Provincial de Barcelona - Servicio de Oncologia, Barcelona

Hospital Universitari Vall d'Hebron - Dept of Oncology, Barcelona

ICO l´Hospitalet - Hospital Duran i Reynals - Servicio de Oncologia, Barcelona

All Listed Sponsors
collaborator

Merck KGaA, Darmstadt, Germany

INDUSTRY

lead

EMD Serono Research & Development Institute, Inc.

INDUSTRY

NCT04551950 - Bintrafusp Alfa Combination Therapy in Participants With Cervical Cancer (INTR@PID 046) | Biotech Hunter | Biotech Hunter