Proximal Resistance Training for People With Multiple Sclerosis

NACompletedINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

October 12, 2020

Primary Completion Date

October 31, 2022

Study Completion Date

October 31, 2022

Conditions
Multiple Sclerosis
Interventions
OTHER

Proximal Resistance Training

Participants will be prescribed 5 categories of resistance exercises, and each category will have a series of exercises to select from. Two will target hip abduction, two will target trunk muscles, and one will target functional resistance training for the hip and trunk during walking-related tasks such as multi-directional resisted walking. Dosing will be based on guidelines for MS. Strengthening exercises will begin with 3 sets of 12-15 reps at 15 rep-max load (RM) and progress to 3 sets of 8-10 reps at 10-12 RM. Endurance exercises requiring a static hold will progress from 3 sets of 15-20 second holds to 30-second holds. Functional resistance will be dosed to improve muscular endurance: 3 sets of 15-20 reps based on form fatigue.

Trial Locations (1)

80045

University of Colorado, Aurora

All Listed Sponsors
collaborator

National Institute of Neurological Disorders and Stroke (NINDS)

NIH

collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

collaborator

National Institutes of Health (NIH)

NIH

lead

University of Colorado, Denver

OTHER

NCT04548154 - Proximal Resistance Training for People With Multiple Sclerosis | Biotech Hunter | Biotech Hunter