Physiologic Accelerated Pacing as a Treatment in Patients With Heart Failure With Preserved Ejection Fraction

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

February 23, 2021

Primary Completion Date

May 16, 2023

Study Completion Date

May 25, 2023

Conditions
Heart Failure, Diastolic
Interventions
DEVICE

Dual chamber pacemaker

Dual chamber pacemaker implantation with Bachmann's bundle lead and His bundle lead placement.

OTHER

Accelerated Physiologic Pacing

The lower rate limit will be programmed to an individualized heart rate.

OTHER

Nocturnal Pacing

In addition to adjustment of the lower rate limit to an individualized heart rate, nocturnal pacing a moderate HR elevation of 110bpm will be implemented between 8pm and 6am.

Trial Locations (1)

05401

University of Vermont Medical Center, Burlington

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Medtronic

INDUSTRY

lead

Daniel L Lustgarten

OTHER