NCT04539002View on ClinicalTrials.gov

Aerobic Exercise for Remyelination in Multiple Sclerosis

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

April 29, 2021

Primary Completion Date

March 27, 2025

Study Completion Date

March 27, 2025

Conditions
Multiple SclerosisSclerosisDemyelinating DiseasesAutoimmune Diseases of the Nervous SystemNervous System DiseasesDemyelinating Autoimmune Diseases, CNSExercise
Interventions
BEHAVIORAL

Aerobic exercise

Aerobic exercise performed on a stationary ergometer for 30 minutes, thrice weekly, with graded supervision. Participants will participate in the intervention over 24 weeks.

BEHAVIORAL

Education Group Control

A monthly, hour-long, class over various MS topics and symptoms, led by a trained facilitator.

Trial Locations (1)

97239

Oregon Health & Science University, Portland

Sponsors
All Listed Sponsors
collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

collaborator

Portland VA Medical Center

FED

collaborator

Oregon Clinical and Translational Research Institute

OTHER

collaborator

Myelin Repair Foundation

UNKNOWN

collaborator

EMD Serono

INDUSTRY

collaborator

Medical Research Foundation, Oregon

OTHER

lead

Oregon Health and Science University

OTHER