Tidal Volume Challenge and Lung Recruitment Maneuver (TIDALREC): the Reliability of Pulse Pression Variation or Stroke Volume Variation on Fluid Responsiveness.

NACompletedINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

November 15, 2020

Primary Completion Date

July 17, 2021

Study Completion Date

July 17, 2021

Conditions
Fluid ChallengeHemodynamic Monitoring
Interventions
PROCEDURE

Starting LRM (Lung Recruitment Maneuver)

The LRM is performed first for 30 seconds (an insufflation pressure of 30 cmH2O for 30 seconds is applied). After a free interval of 3 minutes, the VtC is done during 1 minute. For VtC, tidal volume is increased from 6 to 8 ml.kg-1 of predicted body weight. Finally, after a new free interval of 3 minutes, the fluid challenge (consisting in fluid administration of 250 ml of Ringer Lactate) is started for 10 minutes (in aim to determine which patients are responders). This sequence is repeated every 30 minutes (maximum four times).

PROCEDURE

Starting VtC (Tidal Volume Challenge)

The VtC is performed first for 1 minute. After a free interval of 3 minutes, the LRM is done for 30 seconds. Finally, after another free interval of 3 minutes, the fluid challenge is started for 10 minutes. This sequence is repe-tead every 30 minutes (maximum four times).

Trial Locations (1)

59037

Hop Claude Huriez Chu Lille, Lille

All Listed Sponsors
lead

University Hospital, Lille

OTHER

NCT04535115 - Tidal Volume Challenge and Lung Recruitment Maneuver (TIDALREC): the Reliability of Pulse Pression Variation or Stroke Volume Variation on Fluid Responsiveness. | Biotech Hunter | Biotech Hunter