Phase I Trial of a Recombinant SARS-CoV-2 Vaccine (Sf9 Cell)

PHASE1CompletedINTERVENTIONAL
Enrollment

168

Participants

Timeline

Start Date

August 28, 2020

Primary Completion Date

October 28, 2020

Study Completion Date

November 23, 2021

Conditions
COVID-19
Interventions
BIOLOGICAL

Two doses of middle-dose recombinant SARS-CoV-2 vaccine (Sf9 Cell) at the schedule of day 0, 28

Two doses of middle-dose (20µg/ 0.5ml) recombinant SARS-CoV-2 vaccine (Sf9 Cell) at the schedule of day 0, 28.

BIOLOGICAL

Two doses of high-dose recombinant SARS-CoV-2 vaccine (Sf9 Cell) at the schedule of day 0, 28

Two doses of high-dose (40µg/ 1.0ml) recombinant SARS-CoV-2 vaccine (Sf9 Cell) at the schedule of day 0, 28.

BIOLOGICAL

Three doses of high-dose recombinant SARS-CoV-2 vaccine (Sf9 Cell) at the schedule of day 0, 14, 28

Three doses of high-dose (40µg/ 1.0ml) recombinant SARS-CoV-2 vaccine (Sf9 Cell) at the schedule of day 0, 14, 28

BIOLOGICAL

Two doses of placebo at the schedule of day 0, 28(middle-dose group)

Two doses of placebo (0.5ml) at the schedule of day 0, 28

BIOLOGICAL

Two doses of placebo at the schedule of day 0, 28(high-dose group)

Two doses of placebo (1.0ml) at the schedule of day 0, 28

BIOLOGICAL

Three doses of placebo at the schedule of day 0, 14, 28(high-dose group)

Three doses of placebo (1.0ml) at the schedule of day 0, 14, 28

Trial Locations (1)

210009

Jiangsu Provincial Center for Diseases Control and Prevention, Nanjing

All Listed Sponsors
collaborator

West China Hospital

OTHER

lead

Jiangsu Province Centers for Disease Control and Prevention

NETWORK

NCT04530656 - Phase I Trial of a Recombinant SARS-CoV-2 Vaccine (Sf9 Cell) | Biotech Hunter | Biotech Hunter