Methylene Blue and Postoperative Neurocognitive Disorders

NACompletedINTERVENTIONAL
Enrollment

314

Participants

Timeline

Start Date

May 1, 2021

Primary Completion Date

April 30, 2023

Study Completion Date

December 30, 2024

Conditions
Postoperative Delirium
Interventions
DRUG

Methylene Blue

Intraoperative infusion of 2mg/kg MB after induction of anesthesia for 1 h and 1mg/kg MB with 30 min before the end of surgery

DRUG

Placebo

Equal volume of normal saline after induction of anesthesia for 1 h and Equal volume of normal saline within 30 min before the end of surgery

Trial Locations (1)

Unknown

Shanghai Cancer Center, Fudan University, Shanghai

All Listed Sponsors
lead

Fudan University

OTHER