Efficacy of Augmentation of Cognitive Behavioral Therapy With Transcranial Direct Current Stimulation for Obsessive-Compulsive Disorder (OCD)

NARecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

October 26, 2020

Primary Completion Date

June 30, 2024

Study Completion Date

August 30, 2024

Conditions
Obsessive-Compulsive Disorder
Interventions
COMBINATION_PRODUCT

ERP combined with high-definition active tDCS

"The active tDCS +ERP referred to a period of tDCS applied in the first 20 minutes of the ERP treatment (the tDCS device was activated when ERP began and deactivated automatically while ERP continued). The total treatment phase lasted eight weeks and included ten sessions with experienced psychotherapists following a specific manual for the tDCS+ERP treatment.~The tDCS device will deliver a direct current of 1.5mA during 20 minutes. Anode electrode will be localized in front of the mPFC on the FpZ point according to the EEG international reference. Four cathode electrodes will be placed around (i.e. AF7, AF8, F3, F4)."

COMBINATION_PRODUCT

ERP combined with sham tDCS

Patients will get the same CBT setting as the active tDCS group and they were applied the sham tDCS cocurrently with ERP. The sham tDCS device is the same as the active comparator's except that the sham tDCS will only deliver a current stimulation for the first and last 15 seconds in order to produce somatic sensation in patients similar to that induced by the active tDCS.

Trial Locations (1)

200030

RECRUITING

Shanghai Mental Health Center, Shanghai

All Listed Sponsors
lead

Shanghai Mental Health Center

OTHER