80
Participants
Start Date
April 1, 2019
Primary Completion Date
April 1, 2021
Study Completion Date
June 1, 2021
Epidural anesthesia with light general anesthesia
"Epidural anaesthesia: mixture of ropivacaine 6.5 mg/ml and fentanyl 8.3 μg/ml.~Light general anesthesia: isoflurane in mixture of 50/50 of nitrous oxide and oxygen to achieve Minimum alveolar concentration between 0.6 and 0.8."
Postoperative epidural analgesia
Before the end of operation was given 4 ml of the mixture of ropivacaine 4.4 mg/ml and morphine 0.8mg/ml. Epidural analgesia was continued for next 24 hours with a mixture of ropivacaine 2.2 mg/ml and morphine 0.4 mg/ml.
General anesthesia
"Maintaining general anesthesia: nitrous oxide and oxygen in mixture 50/50 and isoflurane to achieve minimum alveolar concentration between 0.8 and 1.~Fentanyl loading dose: 6-8 μg/kg. Additional fentanyl doses were given incrementally."
Continuous intravenous analgesia
Tramadol 100 mg in the first hour followed by tramadol 300 mg continuously for the next 24 hours.
University Hospital Split, Split
University Hospital of Split
OTHER