NCT04515056View on ClinicalTrials.gov

Characterization of New Human Models of Non-histaminergic Itch

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

September 1, 2020

Primary Completion Date

June 1, 2021

Study Completion Date

June 1, 2021

Conditions
PapainItchSkin Prick Test (SPT)
Interventions
DRUG

Papain 10 µg

The area will be exposed to 10 µg of papain.

DRUG

Papain 50 µg

The area will be exposed to 50 µg of papain.

DRUG

Papain 100 µg

The area will be exposed to 100 µg of papain.

OTHER

Vehicle

The area will be exposed to vehicle

DRUG

Papain 1 SPT

Papain will be applied by 1 SPT prick thought the skin

DRUG

Papain 5 SPT

Papain will be applied by 5 SPT pricks thought the skin

DRUG

Papain 25 SPT

Papain will be applied by 25 SPT pricks thought the skin

OTHER

Cowhage

The last area will be exposed to cowage spicules (made chemically inert by autoclaving) soaked in 5 mg/ml papain solution.

Trial Locations (1)

9000

Aalborg University, Aalborg

All Listed Sponsors
lead

Aalborg University

OTHER

NCT04515056 - Characterization of New Human Models of Non-histaminergic Itch | Biotech Hunter | Biotech Hunter