Dynamic Proteomics and Integrated Rates of Muscle Protein Synthesis During an Acute Period of Loading and Unloading

NAActive, not recruitingINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

December 30, 2021

Primary Completion Date

September 1, 2022

Study Completion Date

July 1, 2025

Conditions
ProteomicsExerciseAtrophy, DisuseHypertrophy
Interventions
PROCEDURE

Knee bracing

Participants will have one leg immobilized, by means of a removable Don Joy Knee Brace. Participants will be expected to keep the knee brace on for 14 days, completely prevent weight bearing on the immobilized leg, and use crutches.

OTHER

Unilateral Resistance Exercise Training

Participants will perform resistance training on 4 occasions throughout an 8 day time period.

Trial Locations (1)

L8S 4K1

Exercise Metabolism Research Laboratory, McMaster Univeristy, Hamilton

All Listed Sponsors
lead

McMaster University

OTHER