A Trial of the Efficacy and the Safety of RO6889450 (Ralmitaront) vs Placebo in Patients With an Acute Exacerbation of Schizophrenia or Schizoaffective Disorder

PHASE2CompletedINTERVENTIONAL
Enrollment

287

Participants

Timeline

Start Date

September 8, 2020

Primary Completion Date

June 21, 2022

Study Completion Date

June 21, 2022

Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
DRUG

RO6889450

Participants will receive oral RO6889450 QD.

DRUG

Placebo

Participants will receive oral placebo QD.

DRUG

Risperidone

Participants will receive oral risperidone QD.

Trial Locations (40)

20708

Communal Non-Commercial Enterprise Cherkasy Regional Psychiatric Hospital of Cherkasy RC, Smila

20877

CBH Health LLC, Gaithersburg

21037

Communal NPE Vinnytsia Reg. Clin. Psychoneurolog. Hosp. n.a. O.I. Yushchenko of Vinnytsia RC, Vinnytsia

30331

Atlanta Center For Medical Research, Atlanta

33016

Galiz Research, LLC, Hialeah

33122

Premier Clinical Research Institute - Miami - BTC - PPDS, Miami

33319

Innovative Clinical Research, Inc., Lauderhill

33334

Research Centers of America - ERG, Oakland Park

36030

Poltava Regional Psychiatry Hospital, Poltava

44718

Neuro-Behavioral Clinical Research, Inc., Canton

45415

Midwest Clinical Research Center - ERG - PPDS, Dayton

60640

Uptown Research Institute, Chicago

61068

Communal Non-Commercial Enterprise of Kharkiv RC Regional clinical psychiatric hospital #3, Kharkiv

72211

Woodland International Research Group Inc., Little Rock

73488

Public NPE Kherson Regional Institution of Mental Care of Kherson RC, Kherson

75042

Pillar Clinical Research LLC, Garland

78754

Community Clinical Research Inc., Austin

90230

ProScience Research Group, Culver City

90660

CNRI - Los Angeles, LLC, Pico Rivera

90706

CITrials, Inc., Bellflower

91206

California Clinical Trials Medical Group managed by Parexel, Glendale

91402

ASCLEPES Research Centers, Panorama City

91403

Schuster Medical Research Institute, Sherman Oaks

91945

Synergy San Diego, Lemon Grove

92102

California Neuropsychopharmacology Clinical Research Institute, LLC, San Diego

92103

Artemis Institute For Clinical Research LLC - San Diego - ClinEdge - PPDS, San Diego

92506

CITrials, Inc., Riverside

92845

Collaborative Neuroscience Network, Inc., Garden Grove

92868

NRC Research Institute, Orange

188357

Psychiatry Hospital #1 n.a. P.P.Kashchenko, Saint Petersburg

188820

Leningradskiy Regional Psychoneurologic Dispensary, Saint Petersburg

190121

Psychiatric Hospital St Nicholas the Wonderworker, Saint Petersburg

192019

FSBI National Medical Research Centre of Psychiatry and Neurology n.a. V.M. Bekhterev of MoH of RF, Sankt-peterburg

197341

City Psychiatry Hospital #3 n.a. I.I. Skvortsov-Stepanov, Saint Petersburg

357034

Stavropol Regional Psychiatry Hospital #2, Stavropol

410060

Saratov regional clinical psychoneurological hospital St Sofii, Saratov

634009

Tomsk National Scientific Medical Center of Russian Academy of Sciences, Tomsk

187-8551

National Center of Neurology and Psychiatry, Tokyo

470-1168

Seishinkai Okehazama Hospital Fujita Kokoro Care Center, Toyoake

04080

Kyiv Medical Regional Union Psychiatry, Kylv

All Listed Sponsors
lead

Hoffmann-La Roche

INDUSTRY

NCT04512066 - A Trial of the Efficacy and the Safety of RO6889450 (Ralmitaront) vs Placebo in Patients With an Acute Exacerbation of Schizophrenia or Schizoaffective Disorder | Biotech Hunter | Biotech Hunter