Imaging Properties of PET Radiotracer [18F]3F-PHPG in Patients With Neuroendocrine Tumors

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

October 19, 2020

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Neuroendocrine Tumors
Interventions
DRUG

3-[18F]Fluoro-para-hydroxyphenethylguanidine

Single IV injection of 12.0 mCi (+/- 10%) \[18F\]3F-PHPG

DRUG

[123I] metaiodobenzylguanidine

Single IV injection of 10.0 mCi \[123I\]MIBG

DIAGNOSTIC_TEST

Positron emission tomography/computed tomography scan

Whole-body PET/CT scan performed at two time-points: 1.5 hours and 3 hours after IV injection of \[18F\]3F-PHPG

DIAGNOSTIC_TEST

Planar scintigraphy scan

Whole-body scan using planar scintigraphy with a gamma camera performed the day after IV injection of \[123I\]MIBG

DIAGNOSTIC_TEST

Single photon emission computed tomography/computed tomography scan

SPECT/CT scan of the primary neuroendocrine tumor performed the day after IV injection of \[123I\]MIBG

Trial Locations (1)

48109

University of Michigan Rogel Cancer Center, Ann Arbor

All Listed Sponsors
lead

University of Michigan Rogel Cancer Center

OTHER

NCT04510311 - Imaging Properties of PET Radiotracer [18F]3F-PHPG in Patients With Neuroendocrine Tumors | Biotech Hunter | Biotech Hunter