NCT04510168View on ClinicalTrials.gov

Accelerated Non-Atherosclerotic Brain Arterial Aging Relationship to Alzheimer's Disease

CompletedOBSERVATIONAL
Enrollment

238

Participants

Timeline

Start Date

September 18, 2020

Primary Completion Date

April 16, 2024

Study Completion Date

April 17, 2024

Conditions
Alzheimer DiseaseDementia
Interventions
DRUG

11C-ER176

PET imaging to measure 18kDa translocator protein; target imaging dose of up to 20 millicurie (mCi)

DRUG

[F-18]MK-6240

PET imaging to measure tau; target imaging dose of 4 to 5 mCi

DRUG

Florbetaben

PET radioligand that binds to amyloid plaques; target-imaging dose of up to 8.1 mCi

OTHER

Magnetic Resonance Imaging

Brain MRI

Trial Locations (1)

10032

Columbia University Medical Center, New York

All Listed Sponsors
lead

Jose Gutierrez, MD, MPH

OTHER

NCT04510168 - Accelerated Non-Atherosclerotic Brain Arterial Aging Relationship to Alzheimer's Disease | Biotech Hunter | Biotech Hunter