Cardiac and Immune Cell Function in Preeclampsia

CompletedOBSERVATIONAL
Enrollment

86

Participants

Timeline

Start Date

January 7, 2020

Primary Completion Date

March 6, 2024

Study Completion Date

March 6, 2024

Conditions
PreeclampsiaHypertensionPregnancy Induced HypertensionPregnancy RelatedCardiovascular DiseasesCardiovascular Risk FactorHeart Diseases
Interventions
DIAGNOSTIC_TEST

Cardiovascular magnetic resonance

Imaging of the heart with CMR, without use of contrast agents.

DIAGNOSTIC_TEST

Echocardiography

Imaging of the heart with ultrasound.

DIAGNOSTIC_TEST

Blood test

Time- matched blood samples will be taken from patients to assess immune cell phenotype and function, paying particular attention to neutrophil and T-cell phenotype. Plasma samples will be collected for the analyses of cardiac specific factors (BNP, troponin) as well as measurement of steroid hormones (progesterone and oestradiol), and soluble inflammatory and anti-inflammatory mediators

Trial Locations (1)

E1 1BB

Barts Health NHS Trust, The Royal London Hospital, London

All Listed Sponsors
collaborator

British Heart Foundation

OTHER

collaborator

Barts & The London NHS Trust

OTHER

lead

Queen Mary University of London

OTHER

NCT04508582 - Cardiac and Immune Cell Function in Preeclampsia | Biotech Hunter | Biotech Hunter