Efficacy and Safety ofCACXL in the Treatment of Keratoconus With Thin Corneas

NACompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

January 1, 2018

Primary Completion Date

January 1, 2019

Study Completion Date

February 1, 2019

Conditions
Progressive Keratoconus
Interventions
PROCEDURE

contact lens assisted corneal cross linking

40 eyes of 30 patients underwent CACXL. The central 9 mm of corneal epithelium was abraded , Iso-tonic riboflavin 0.1% was applied every 2 minutes for 10 minutes on the debrided cornea. A disposable soft Contact lens without an ultraviolet filter (Soflens, Bausch \& Lomb) was placed in the inferior fornix during soaking of the stroma with riboflavin for 10 minutes. The contact lens was applied on the corneal surface and the cornea was exposed to ultraviolet-A irradiation at fluence of 3.0 mW/cm2 for 30 minutes The uncorrected (UDVA) and best corrected (BDVA) visual acuity, and maximum (K max) keratometric values, were assessed before, and after 9 months CXL. Endothelial cell count was assessed before and 3 months after CXL. Anterior segment OCT was done 1 month after CXL to evaluate the presence and depth of the corneal stromal demarcation line.

Trial Locations (1)

12654

Kasrelaini Hospital, Cairo

All Listed Sponsors
lead

Kasr El Aini Hospital

OTHER

NCT04504578 - Efficacy and Safety ofCACXL in the Treatment of Keratoconus With Thin Corneas | Biotech Hunter | Biotech Hunter