24
Participants
Start Date
April 12, 2021
Primary Completion Date
June 29, 2022
Study Completion Date
July 27, 2022
High-dose accelerated rTMS
A MagVenture MagPro Transcranial Magnetic Stimulation (TMS) System will be utilized. All participants will receive open-label treatment for approximately eight, 3-minute sessions of intermittent theta burst rTMS on each of three days within an eight-day span. A single session = 600 pulses at 120% resting motor threshold (rMT), intermittent Theta Burst Stimulation (iTBS) triplets at 50 Hz for 2 seconds and repeated every 10 seconds for a total of 190 s to left dorsolateral prefrontal cortex. Total pulses = 14,400. To enable adherence and retention, the days do not need to be contiguous. Same day sessions will be separated by 10-15 minutes, but more accounting for participant comfort.
Medical University of South Carolina, Charleston
National Center of Neuromodulation for Rehabilitation
OTHER
Medical University of South Carolina
OTHER