Apoptosis Proteins and Endothelial Dysfunction in Patients With Atherosclerosis of Peripheral Arteries

CompletedOBSERVATIONAL
Enrollment

250

Participants

Timeline

Start Date

January 1, 2020

Primary Completion Date

January 1, 2023

Study Completion Date

November 1, 2023

Conditions
AtherosclerosisEndothelial Dysfunction
Interventions
PROCEDURE

Bypass surgery

Creating a bypass with graft or vein.

PROCEDURE

Endovascular angioplasty/stenting

Performing an angioplasty with or without stenting in stenosis.

PROCEDURE

Hybrid surgery

Performing an angioplasty with or without stenting in stenosis and creating a bypass with graft or vein.

DRUG

Vitamin E

100 mg Vitamin E per os 1 per day (1 month).

DIAGNOSTIC_TEST

Duplex ultrasound

Duplex ultrasound of lower limbs arteries.

DIAGNOSTIC_TEST

Blood sampling

Blood sampling for apoptosis and endothelial dysfunction markers.

DIAGNOSTIC_TEST

Arterial wall sampling

Arterial wall sampling for apoptosis markers.

Trial Locations (1)

Unknown

Ryazan State Medical University, Ryazan

All Listed Sponsors
lead

Ryazan State Medical University

OTHER

NCT04502849 - Apoptosis Proteins and Endothelial Dysfunction in Patients With Atherosclerosis of Peripheral Arteries | Biotech Hunter | Biotech Hunter