Sensory-specific Peripheral Stimulation for Tremor Management

NARecruitingINTERVENTIONAL
Enrollment

180

Participants

Timeline

Start Date

September 1, 2020

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Parkinson's DiseaseEssential Tremor
Interventions
DEVICE

Peripheral electrical stimulation

Electrical stimulation will be delivered to forearm muscles with an electrical stimulator (Digitimer Ltd., Hertfordshire, UK) so that they generate forces opposed to those arising from the tremorgenic input.

DEVICE

Single pulse TMS

Single-pulse TMS (spTMS) will be delivered with a TMS stimulator (MagPro X100 w/ MagOption, MagVenture, Farum, Denmark) and a figure-of-eight TMS coil. An MRI-based TMS navigation system will be used to navigate the TMS coil (Localite, St Augustin, Germany).

Trial Locations (1)

60611

RECRUITING

Shirley Ryan AbilityLab, Chicago

All Listed Sponsors
collaborator

Northwestern University

OTHER

lead

Shirley Ryan AbilityLab

OTHER