NCT04499677 - FLARE: Favipiravir +/- Lopinavir: A RCT of Early Antivirals | Biotech Hunter

Enrollment

240

Participants

Timeline

Start Date

September 24, 2020

Primary Completion Date

December 1, 2021

Study Completion Date

January 17, 2022

Conditions

COVID-19

Interventions

DRUG

Favipiravir

Dosage and method of administration: Day 1: 1800 mg twice daily; Day 2 to Day 7: 400 mg four (4) times daily.

DRUG

Lopinavir/ Ritonavir

Dosage and method of administration: Day 1: 400mg/100 mg twice daily; Day 2 to Day 7: 200mg/50mg four (4) times daily

OTHER

Favipiravir Placebo

Dosage and method of administration: Day 1: 1800 mg twice daily; Day 2 to Day 7: 400 mg four (4) times daily.

OTHER

Lopinavir/ Ritonavir Placebo

Dosage and method of administration: Day 1: 1800 mg twice daily; Day 2 to Day 7: 400 mg four (4) times daily.

Trial Locations (2)

Royal Free Hospital, London

University College London Hospital (UCLH), London

All Listed Sponsors

collaborator

LifeArc

OTHER

lead

University College, London

OTHER