Endogenous vs. Exogenous Ketone Bodies

NACompletedINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

August 21, 2020

Primary Completion Date

July 23, 2021

Study Completion Date

July 23, 2021

Conditions
Healthy
Interventions
DIETARY_SUPPLEMENT

Beta-Hydroxybutyrate as Ca-Mg-salt, active

24 hour intervention with ketone body supplements additional to a normal diet (isocaloric diet in total) to induce ketosis (exogenous ketone bodies), in a metabolic chamber at physical activity level of 1.6, after one day of isocaloric diet in a metabolic chamber at physical activity level of 1.6.

DIETARY_SUPPLEMENT

ketogenic diet (KetoCal® 4:1 Neutral, Nutricia GmbH, Erlangen, Germany), active

24 hour interventions with ketogenic isocaloric diet to induce ketosis (endogenous ketone bodies), in a metabolic chamber at physical activity level of 1.6, after one day of isocaloric diet in a metabolic chamber at physical activity level of 1.6.

DIETARY_SUPPLEMENT

fasting, active

36 hours of fasting, in a metabolic chamber at physical activity level of 1.6, after one day of isocaloric diet in a metabolic chamber at physical activity level of 1.6.

DIETARY_SUPPLEMENT

fasting, inactive

"36 hours of fasting, in a metabolic chamber at physical activity level of 1.3, after one day of isocaloric diet in a metabolic chamber at physical activity level of 1.3.~The same intervention is reproduced one week later."

Trial Locations (1)

24105

Institute of Human Nutrition, Kiel

All Listed Sponsors
lead

University of Kiel

OTHER

NCT04490226 - Endogenous vs. Exogenous Ketone Bodies | Biotech Hunter | Biotech Hunter