Dihydroartemisinin-Piperaquine in the Context of Antiretroviral Therapy

PHASE4CompletedINTERVENTIONAL
Enrollment

194

Participants

Timeline

Start Date

November 23, 2020

Primary Completion Date

April 11, 2022

Study Completion Date

April 11, 2022

Conditions
Drug-Drug InteractionHIV Infection
Interventions
DRUG

Dihydroartemisinin-piperaquine

It is expected that efavirenz (EFV), lopinavir/ritonavir (LPV/r), and/or dolutegravir (DTG) will alter DP exposure.

Trial Locations (2)

Unknown

Masafu General Hospital (MGH) at Busia District, Eastern Uganda, Masafu

Baylor-Uganda Center of Excellence on Mulago Hospital Complex and Masafu General Hospital, Kampala

All Listed Sponsors
collaborator

Yale University

OTHER

collaborator

Makerere University

OTHER

collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

lead

University of California, San Francisco

OTHER

NCT04487145 - Dihydroartemisinin-Piperaquine in the Context of Antiretroviral Therapy | Biotech Hunter | Biotech Hunter