Haplo Peripheral Blood Sct In GVHD Prevention

predetermined dose, intravenously, a predetermined times per cycle Given in both pre stem cell and post stem cell cycles

◦Cyclophosphamide predetermined dose, predetermined number of times in Given in pre-stem cell Regimen #1 Cyclophosphamide predetermined dose, predetermined number of times in cycle, intravenous infusion

Total body irradiation (TBI) once per cycle.

Melphalan, infusion, determined dosage, once per cycle

Sirolimus: Predetermined dosage, predetermined number of time in cycle, oral: Please note that doses of sirolimus can be adjusted at the treating physician's discretion given the multiple drugs and other situations which affect its metabolism

◦Mycophenolate mofetil, oral or iv(predetermined dose or IV TID (based upon actual body weight), at predetermined times per cycle

IV, predetermined dose, weekly to 6 total doses

◦Given in Post Stem Cell cycle of Regimen #1 and #2 Cyclophosphamide predetermined dose, predetermined number of times in cycle, intravenous infusion