A Study to Evaluate Efficacy, Safety, and Immunogenicity of mRNA-1273 Vaccine in Adults Aged 18 Years and Older to Prevent COVID-19

PHASE3CompletedINTERVENTIONAL
Enrollment

30,415

Participants

Timeline

Start Date

July 27, 2020

Primary Completion Date

December 29, 2022

Study Completion Date

December 29, 2022

Conditions
SARS-CoV-2
Interventions
BIOLOGICAL

mRNA-1273

Sterile liquid for injection

BIOLOGICAL

Placebo

0.9% sodium chloride (normal saline) injection

Trial Locations (100)

10010

Weill Cornell Chelsea - (CRS), New York

10065

Weill Cornell Medical College, New York

13901

Meridian Clinical Research, Binghamton

15213

UPMC University Center, Pittsburgh

19104

University of Pennsylvania, Philadelphia

20037

George Washington University, Washington D.C.

20850

Synexus - Optimal Research - Rockville, Rockville

20854

Meridian Clinical Research, Rockville

21201

University of Maryland School of Medicine, Baltimore

27157

Wake Forest University Health Sciences, Winston-Salem

27599

University of North Carolina at Chapel Hill, Chapel Hill

27612

M3 Wake Research, Inc - M3 Wake, Raleigh

28210

Tryon Medical Partners, Charlotte

28304

Carolina Institute for Clinical Research - M3 Wake Research, Fayetteville

28403

Trial Management Associates, Wilmington

29303

Keystone VitaLink Research - Spartanburg, Spartanburg

29464

Coastal Carolina Research Center, Mt. Pleasant

29615

Keystone VitaLink Research - Greenville, Greenville

29621

Keystone VitaLink Research, Anderson

30030

Hope Clinic of The Emory Vaccine Center, Decatur

30281

Clinical Research Atlanta, Stockbridge

30303

Grady Health System, Atlanta

30322

Children's Healthcare of Atlanta, Atlanta

31406

Meridian Clinical Research, Savannah

32216

Jacksonville Center for Clinical Research, Jacksonville

32720

Accel Research Site, DeLand

32806

Synexus Clinical Research US, Inc. - Orlando, Orlando

32934

Synexus - Optimal Research - Melbourne, Melbourne

33024

Research Centers of America, Hollywood

33135

Suncoast Research Group, Miami

33136

University of Miami, Miami

33409

Palm Beach Research Center, West Palm Beach

35205

Ascension St. Vincent Birmingham, Birmingham

35211

Synexus Clinical Research US, Inc. - Birmingham, Birmingham

37232

Vanderbilt University Medical Center, Medical Arts Building, Nashville

Vanderbilt University Medical Center, Medical Center North, Nashville

37421

WR-ClinSearch, Chattanooga

39465

MediSync Clinical Research Hattiesburg Clinic, Petal

39720

Alliance for Multispecialty Research, Knoxville

44122

Rapid Medical Research Inc, Cleveland

45236

Synexus Clinical Research US, Inc. - Cincinnati, Cincinnati

45242

New Horizons Clinical Research, Cincinnati

45267

Cincinnati CRS, Cincinnati

48202

Henry Ford Health System, Detroit

57049

Meridian Clinical Research, Dakota Dunes

60602

Synexus Clinical Research US, Inc. - Chicago, Chicago

60612

UIC Project WISH CRS, Chicago

60637

University of Chicago-Hospital, Chicago

63104

Saint Louis University, St Louis

63141

Sundance Clinical Research, St Louis

66219

Johnson County Clin-Trials, Lenexa

67114

Alliance for Multispecialty Research, Newton

67207

Alliance for Multispecialty Research- East Wichita, Wichita

68134

Meridian Clinical Research, Omaha

68701

Meridian Clinical Research, Norfolk

68803

Meridian Clinical Research, Grand Island

70006

Benchmark Research - Metairie, Metairie

70808

Meridian Clinical Research, Baton Rouge

72205

Baptist Health Center for Clinical Research, Little Rock

73112

Lynn Health Science Institute, Oklahoma City

75224

Global Medical Research - M3 Wake Research, Dallas

75234

Synexus Clinical Research US, Inc. - Dallas, Dallas

76135

Benchmark Research - Fort Worth, Fort Worth

76904

Benchmark Research - San Angelo, San Angelo

77030

Baylor College of Medicine, Houston

77081

DM Clinical Research - Texas Center For Drug Development, Houston

77375

DM Clinical Research, Tomball

77555

University of Texas Medical Branch at Galveston, Galveston

78041

Laguna Clinical Research, Laredo

78229

Clinical Trials of Texas, Inc, San Antonio

78504

Centex Studies, McAllen

78613

Advanced Clinical Research - Be Well MD, Cedar Park

78705

Benchmark Research - Austin, Austin

Synexus - Optimal Research - Austin, Austin

78745

Tekton Research, Austin

80045

University of Colorado Hospital, Aurora

80918

Lynn Institute of The Rockies, Colorado Springs

84109

Foothill Family Clinic - North, Salt Lake City

84121

Foothill Family Clinic-South Clinic, Salt Lake City

84123

Synexus Clinical Research US, Inc. - Salt Lake City, Murray

85018

Hope Research Institute, Peoria

Hope Research Institute, Phoenix

85224

Hope Research Institute, Chandler

85306

Synexus Clinical Research US, Inc. - Phoenix West, Glendale

85712

Quality of Life Medical and Research Center, Tucson

89104

Clinical Research Center of Nevada, Las Vegas

89119

AB Clinical Trials, Las Vegas

90038

UCLA Vine Street Clinic CRS, Los Angeles

90073

VA Greater Los Angeles Healthcare (veterans only), Los Angeles

91942

eStudySite - La Mesa, La Mesa

92093

University of California San Diego, La Jolla

92108

Medical Center For Clinical Research - M3 Wake Research, San Diego

92220

Advanced Clinical Research - Rancho Paseo, Banning

95864

Benchmark Research - Sacramento, Sacramento

96001

Paradigm Clinical Research Institute Inc, Redding

97504

Crisor, Medford

98101

Kaiser Permanente - Seattle, Seattle

02115

Brigham and Women's Hospital, Boston

07601

Hackensack University Medical Center, Hackensack

07103

New Jersey Medical School, Newark

All Listed Sponsors
collaborator

Biomedical Advanced Research and Development Authority

FED

collaborator

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

lead

ModernaTX, Inc.

INDUSTRY

NCT04470427 - A Study to Evaluate Efficacy, Safety, and Immunogenicity of mRNA-1273 Vaccine in Adults Aged 18 Years and Older to Prevent COVID-19 | Biotech Hunter | Biotech Hunter