Abaloparatide Added to Ongoing Denosumab vs Continued Denosumab Alone

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

February 1, 2021

Primary Completion Date

September 1, 2026

Study Completion Date

December 1, 2026

Conditions
Osteoporosis, Postmenopausal
Interventions
DRUG

Denosumab Injection

Denosumab alone: 3 injections of Denosumab at appropriate times, separated by no more than 7 months from the last treatment.

DRUG

Abaloparatide

Combination therapy: 3 injections of Denosumab at appropriate times, separated by no more than 7 months from the last treatment, with added abaloparatide 80 mcg subcutaneously daily, started within 6 months of the last denosumab treatment, for a total of 18 months.

Trial Locations (1)

10021

Hospital for Special Surgery, New York

All Listed Sponsors
collaborator

Radius Health, Inc.

INDUSTRY

collaborator

Crozer-Keystone Health System

OTHER

lead

Hospital for Special Surgery, New York

OTHER