60
Participants
Start Date
July 15, 2020
Primary Completion Date
February 28, 2024
Study Completion Date
March 30, 2024
Hydroxyethyl Starch 130-0.4 60 MG/ML [Voluven]
Hydroxyethyl starch dose is 500 cc in 6 hours
Hydrocortisone
Hydrocortisone dose is 200-300 mg /day intravenously
Placebo
received the standard ALP treatment according to TUPTC protocol as follows: patient resuscitation, care of airway, breathing and circulation, gastric decontamination with 2 ampoules sodium bicarbonate (each ampoule 25 ml containing 2.1 gm sodium bicarbonate) followed by activated charcoal in dose of 1 g/Kg orally, adequate hydration, normal saline administration (0.9% Sodium Chloride IV), vasopressors IV infusions, inhalation of 100% oxygen, ranitidine IV, magnesium sulfate IV infusion and other supportive treatment.
Tarek Abdel Hay, Tanta
Tanta University
OTHER