The Effect of Consecutive Fecal Microbiota Transplantation on Non-Alcoholic Fatty Liver Disease (NAFLD)

PHASE4UnknownINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

December 10, 2019

Primary Completion Date

March 31, 2021

Study Completion Date

December 31, 2021

Conditions
NAFLD
Interventions
OTHER

Gut microbiome transplantation

Fecal transplantation will be performed at baseline and at week 3 and 6. At the Department of Clinical Bacteriology either the autologous or allogenic feces is prepared for donation by an experienced lab co-worker. The fecal transplantation will be performed via gastroduodenal endoscopy at the Department of Gastroenterology by an experienced endoscopist. To alleviate the procedure, midazolam is offered to the participants. Following placement of the endoscope in the horizontal duodenum, 150 mL feces solution is inserted via the endoscope.

Trial Locations (1)

2333 ZA

RECRUITING

Leiden University Medical Center, Leiden

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Dutch Donor Feces Bank

UNKNOWN

collaborator

Vedanta Biosciences

UNKNOWN

lead

Leiden University Medical Center

OTHER