Rotational Thromboelastometry Guided Blood Component Use in Children With Cirrhosis Undergoing Invasive Procedures: A Randomized Controlled Trial

NACompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

November 16, 2020

Primary Completion Date

March 28, 2022

Study Completion Date

March 28, 2022

Conditions
Cirrhosis, Liver
Interventions
PROCEDURE

Rotational Thromboelastometry to guide blood product transfusion pre invasive procedure

"Rotational Thromboelastometry will be performed pre procedure and blood component will be transfused if~* EXTEM CT more than 80 sec then FFP will be transfused at 15 ml/kg MCF less than 35 mm then Platelet will be transfused at 10 ml/kg~* FIBTEM MCF less than 7 mm then Cryoprecipitate will be transfused at 5 ml/kg"

PROCEDURE

Conventional transfusion methods to guide blood product transfusion pre invasive procedure

Transfusion will be given If INR: 1.5 - 2.5 FFP will be transfused at 10 ml/kg If Platelet Count is 20,000/mm3-50,000/mm3 Platelet will be transfused at 10 ml/kg If Fibrinogen \< 80 mg/dl Cryoprecipitate will be transfused at 5 ml/kg

Trial Locations (1)

110070

Institute of Liver and Biliary Sciences, New Delhi

All Listed Sponsors
lead

Institute of Liver and Biliary Sciences, India

OTHER

NCT04460222 - Rotational Thromboelastometry Guided Blood Component Use in Children With Cirrhosis Undergoing Invasive Procedures: A Randomized Controlled Trial | Biotech Hunter | Biotech Hunter