Noninvasive Assessment of Myocardial Stiffness by 2D-SWE Ultrasound Technique (Bidimensional Shear Wave Elastography) in Patients With Transthyretin Amyloidosis

NAUnknownINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

June 3, 2020

Primary Completion Date

January 31, 2021

Study Completion Date

May 29, 2021

Conditions
Amyloidosis
Interventions
PROCEDURE

Shear wave elastography

The elastographic technique by ultrasound (USE), shear waves or shear wave elastography (SWE), quantitatively evaluates tissue stiffness by mapping the propagation of acoustic waves (shear waves), in a non-invasive manner and without emission of ionizing radiation. Their speeds are tracked by the ultrasound equipment after tissue deformation occurs, generated by pulses of acoustic radiation (ARFI) of the transducer itself. Assuming the correlation between tissue stiffness and increased acoustic propagation speeds, it is possible to describe mathematically the elasticity of tissues by measuring specific acoustic waves.

Trial Locations (1)

05403-000

RECRUITING

University of Sao Paulo Medical School - The Heart Institute, São Paulo

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Pfizer

INDUSTRY

lead

Fábio Fernandes

OTHER

NCT04456582 - Noninvasive Assessment of Myocardial Stiffness by 2D-SWE Ultrasound Technique (Bidimensional Shear Wave Elastography) in Patients With Transthyretin Amyloidosis | Biotech Hunter | Biotech Hunter