NCT04454476View on ClinicalTrials.gov

Reversal of Preneoplastic Metaplasia in the Stomach With MEK Inhibitor

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

November 9, 2022

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2025

Conditions
Gastric CancerMetaplasiaStage I Gastric CancerInitial-onset Gastric Cancer
Interventions
DRUG

Trametinib treatment

1 mg taken by mouth once a day for 14 days

PROCEDURE

Endoscopy

A tiny camera on the end of a long, flexible tube will be used to examine the stomach and take biopsies.

Trial Locations (3)

Unknown

Nagasaki University Hospital, Nagasaki

Nihon University School of Medicine, Tokyo

University of Tokyo Medical Center, Tokyo

All Listed Sponsors
lead

Vanderbilt-Ingram Cancer Center

OTHER