NCT04454203 - Femoral Peri-arterial Local Anesthetic Injection Via Peri-arterial Perineural Catheter Reverses Tourniquet Associated Ischemic Hypertension | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

February 5, 2021

Primary Completion Date

February 1, 2026

Study Completion Date

February 3, 2026

Conditions

Tourniquet HypertensionIntraoperative HypertensionTotal Ankle ArthroplastyAnkle Fusion

Interventions

DRUG

Mepivacaine

An infiltration of mepivacaine superomedially to the femoral artery via perineural catheter.

DRUG

Saline

An infiltration of saline superomedially to the femoral artery via perineural catheter.

PROCEDURE

Perifemoral Injection of Local Anesthetic

Infiltration of mepivacaine superomedially to the formal artery via perineural catheter in an effort to numb the nerves that contribute to tourniquet hypertension intraoperatively.

PROCEDURE

Perifemoral Injection of Local Anesthetic

Infiltration of saline superomedially to the formal artery via perineural catheter that should NOT numb the nerves that contribute to tourniquet hypertension intraoperatively.

Trial Locations (1)

27710

RECRUITING

Duke University Hospital, Durham