Low Dose Empagliflozin in Adults With Type 1 Diabetes on Closed Loop Insulin System

PHASE1CompletedINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

November 2, 2020

Primary Completion Date

January 5, 2022

Study Completion Date

January 13, 2022

Conditions
Type 1 Diabetes
Interventions
DRUG

14-day outpatient intervention

The patient will be on the closed-loop insulin system and the intervention drug (placebo, empagliflozin 2.5 mg, or empagliflozin 5 mg) for 14 days. Insulin reductions will be made to avoid hypoglycemia with the drug agent. Remote contact around Day 4 (+/- 2 days) will be made to optimize insulin settings. The last 10 days will be used to assess continuous glucose monitoring data during each intervention. A wash-out period of 7 - 21 days will separate each intervention.

Trial Locations (1)

H4A 3T2

Clinique Médicale Hygea, Montreal

All Listed Sponsors
lead

McGill University

OTHER

NCT04450563 - Low Dose Empagliflozin in Adults With Type 1 Diabetes on Closed Loop Insulin System | Biotech Hunter | Biotech Hunter