NCT04448327View on ClinicalTrials.gov

Impact of Transcutaneous Vagal Nerve Stimulation on Stress Response in Major Depression

NARecruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

January 29, 2021

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Major Depressive Disorder
Interventions
DEVICE

active tVNS

non-painful electrical stimulation of the auricle for 30 minutes during a functional magnetic resonance imaging session

DEVICE

Sham tVNS

Sham stimulation of the auricle for 30 minutes during a functional magnetic resonance imaging session

Trial Locations (1)

02129

RECRUITING

Massachusetts General Hospital, Charlestown

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

Massachusetts General Hospital

OTHER