Mechanisms of Fatigability With Diabetes

NARecruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

September 1, 2022

Primary Completion Date

July 1, 2027

Study Completion Date

August 31, 2027

Conditions
Pre-diabetesType 2 Diabetes
Interventions
OTHER

Control Exercise

Each participant will attend 3 sessions per week for 8 weeks. Participants will perform low-load knee extension resistance training (20% of 1-RM) without blood flow restriction on the designated leg for 4 sets of contractions with 15 contractions per set of contractions with a 30 second rest between each set of contractions.

OTHER

Blood Flow Restriction Exercise

Each participant will attend 3 sessions per week for 8 weeks. Participants will perform low-load knee extension resistance training (20% of 1-RM) with blood flow restriction on the designated leg for 4 sets of contractions with 15 contractions per set of contractions with a 30 second rest between each set of contractions.

Trial Locations (1)

48109

RECRUITING

University of Michigan, Ann Arbor

All Listed Sponsors
collaborator

University of Illinois at Chicago

OTHER

collaborator

Medical College of Wisconsin

OTHER

collaborator

University of Wisconsin, Madison

OTHER

collaborator

National Institute on Aging (NIA)

NIH

collaborator

Marquette University

OTHER

lead

University of Michigan

OTHER