CRPS - Diagnostics, Pathophysiological Mechanisms, and Response to Treatment With Noninvasive Brain Stimulation

NACompletedINTERVENTIONAL
Enrollment

62

Participants

Timeline

Start Date

August 28, 2017

Primary Completion Date

July 29, 2021

Study Completion Date

August 25, 2022

Conditions
Transcranial Magnetic StimulationComplex Regional Pain Syndrome of Upper Limb (Disorder)
Interventions
DEVICE

Sham nrTMS and open phase

"Navigated repetitive TMS treatment (10 sessions during a three-week period) randomized to sham. In the following open phase stimulation the treatment targets are the right S2-contralateral M1-left S2."

DEVICE

Active nrTMS and open phase

"Navigated repetitive TMS treatment (10 sessions during a three-week period) randomized to S2. In the following open phase stimulation the treatment targets are contralateral M1 and left S2. If the patient benefited from active S2 stimulation, but the treatment effect faded in follow-up, the open phase stimulation starts with right S2."

Trial Locations (2)

20014

Turku University Hospital, Pain Clinic, Turku

00029

Helsinki University Hospital, Pain Clinic, Helsinki

All Listed Sponsors
collaborator

Turku University Hospital

OTHER_GOV

lead

Helsinki University Central Hospital

OTHER

NCT04439669 - CRPS - Diagnostics, Pathophysiological Mechanisms, and Response to Treatment With Noninvasive Brain Stimulation | Biotech Hunter | Biotech Hunter