160
Participants
Start Date
October 1, 2019
Primary Completion Date
December 30, 2025
Study Completion Date
December 30, 2025
Microneurography to measure muscle sympathetic nerve activity (MSNA)
Microneurography is a direct measurement of electrical activity of peripheral sympathetic nerves
Baroreflex sensitivity testing
Two arms of the baroreflex that will be tested in this study are sympathetic and cardiovagal. Static baroreflex is tested during baseline resting conditions and dynamic baroreflex is tested during Valsalva maneuvers.
Sympathoexcitatory Maneuvers
Cold Pressor Test (CPT) and Upper extremity fatiguing contraction with post exercise circulatory occlusion (PECO) will be performed
Blood tests
Serum FSH, estrogen, progesterone, and testosterone will be measured
RECRUITING
University of Minnesota, Minneapolis
University of Minnesota
OTHER