NCT04433390View on ClinicalTrials.gov

Effect of Naloxegol on Postoperative Ileus in Patients Undergoing Cardiac Surgery

PHASE3CompletedINTERVENTIONAL
Enrollment

305

Participants

Timeline

Start Date

October 14, 2020

Primary Completion Date

January 28, 2022

Study Completion Date

March 3, 2022

Conditions
Postoperative Ileus (Post Cardiac Surgery Constipation)
Interventions
DRUG

Naloxegol

one naloxegol 12.5 mg tablet will be administrated 2 hours before surgery. One 25 mg naloxegol tablet per day will be administrated from 24h post-surgery until bowel movement; for maximum 5 days.

DRUG

inert tablet

one inert tablet will be administrated 2 hours before surgery. One inert tablet per day will be administrated from 24h post-surgery until bowel movement; for maximum 5 days.

Trial Locations (1)

92200

CMC Ambroise Paré, Neuilly-sur-Seine

All Listed Sponsors
lead

CMC Ambroise Paré

OTHER

NCT04433390 - Effect of Naloxegol on Postoperative Ileus in Patients Undergoing Cardiac Surgery | Biotech Hunter | Biotech Hunter