NCT04432493View on ClinicalTrials.gov

Using Combined EEG and Non-invasive Brain Stimulation to Examine and Improve Reward Functioning in Opioid Use Disorder

NACompletedINTERVENTIONAL
Enrollment

81

Participants

Timeline

Start Date

February 20, 2020

Primary Completion Date

August 31, 2022

Study Completion Date

August 31, 2022

Conditions
Opioid-use Disorder
Interventions
DEVICE

Active repetitive transcranial magnetic stimulation (rTMS)

rTMS will be used to stimulate neuronal activity of the dorsolateral prefrontal cortex (DLPFC). Participants will receive no more than 2000 pulses of rTMS at 110% of participants' resting motor threshold at 10 Hz continuously for the duration of the t-maze task.

DEVICE

Sham repetitive transcranial magnetic stimulation (rTMS)

Sham TMS will be used to mimic the auditory sensation of the Active rTMS condition. Protocols for the sham condition will be the same as the active condition, however the TMS coil will be flipped 180 degrees so that participants in this condition will not receive any active stimulation.

Trial Locations (1)

07102

Rutgers University - Newark, Newark

All Listed Sponsors
lead

Rutgers University

OTHER

NCT04432493 - Using Combined EEG and Non-invasive Brain Stimulation to Examine and Improve Reward Functioning in Opioid Use Disorder | Biotech Hunter | Biotech Hunter