A Phase II Study of Hepalatide in Subjects With Chronic Hepatitis B

PHASE2CompletedINTERVENTIONAL
Enrollment

96

Participants

Timeline

Start Date

June 18, 2021

Primary Completion Date

November 1, 2023

Study Completion Date

November 29, 2023

Conditions
Hepatitis B, Chronic
Interventions
DRUG

Hepalatide 2.1mg

2.1 mg/day subcutaneously (s.c.) for 24 week

DRUG

Hepalatide 4.2mg

4.2mg/day subcutaneously (s.c.) for 24 week

DRUG

Hepalatide 6.3mg

6.3mg/day subcutaneously (s.c.) for 24 week

DRUG

placebo 2.1mg

2.1 mg/day subcutaneously (s.c.) for 24 week

DRUG

placebo 4.2mg

4.2 mg/day subcutaneously (s.c.) for 24 week

DRUG

placebo 6.3mg

6.3 mg/day subcutaneously (s.c.) for 24 week

DRUG

Pegylated Interferon

180 ug/week subcutaneously (s.c.) for 28 week

Trial Locations (12)

100039

The fifth medical center of PLA, Beijing

Unknown

Jilin Hepatobiliary Disease Hospital, Changchun

The first hospital of Jilin University, Changchun

Chizhou People's Hospital, Chizhou

The First Hospital Affiliated to the Army Medical University, Chongqing

The First Affiliated Hospital of Nanchang University, Nanchang

The Second Hospital of Nanjing, Nanjing

Qingyuan People's Hospital, Qingyuan

Shanghai Tongren Hospital, Shanghai

The Sixth People's Hospital of Shenyang, Shenyang

Henan Provincial People's Hospital, Zhengzhou

Henan Provincial Infectious Disease Hospital, Zhenzhou

All Listed Sponsors
lead

Shanghai HEP Pharmaceutical Co., Ltd.

INDUSTRY