NCT04423627View on ClinicalTrials.gov

Sympathetic Regulation of Large Artery Stiffness in Humans With ISH

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

June 1, 2021

Primary Completion Date

July 31, 2025

Study Completion Date

July 31, 2025

Conditions
Hypertension, SystolicStiffness, Aortic
Interventions
DRUG

Clonidine

Clonidine 0.2 mg/day oral tablet

DRUG

Hydrochlorothiazide

Hydrochlorothiazide 37.5 mg/day oral tablet

DRUG

Placebo

Placebo

Trial Locations (2)

52240

Amy Stroud, Iowa City

52242

University of Iowa, Iowa City

All Listed Sponsors
lead

University of Iowa

OTHER