A Study of Evorpacept (ALX148) With Azacitidine for Higher Risk Myelodysplastic Syndrome (ASPEN-02)

PHASE1TerminatedINTERVENTIONAL
Enrollment

65

Participants

Timeline

Start Date

October 2, 2020

Primary Completion Date

January 17, 2025

Study Completion Date

June 10, 2025

Conditions
Higher Risk Myelodysplastic Syndromes
Interventions
DRUG

evorpacept

Fusion protein that blocks CD47-SIRPalpha pathway

DRUG

azacitidine

Hypomethylating agent (HMA)

Trial Locations (19)

10003

Hospital San Pedro de Alcantara, Cáceres

27710

Duke University Medical Center, Durham

28204

Levine Cancer Institute, Charlotte

37007

Hospital Universitario de Salamanca, Salamanca

37203

Vanderbilt University Medical Center, Nashville

46026

Hospital Universitari i Politecnic La Fe de Valencia, Valencia

46202

IU Simon Cancer Center, Indianapolis

49546

START Midwest, Grand Rapids

55905

Mayo Clinic, Rochester

60611

Northwestern University Feinberg School of Medicine, Chicago

77030

University of Texas MD Anderson Cancer Center, Houston

90033

University of Southern California, Norris Comprehensive Cancer Center, Los Angeles

98109

Fred Hutchinson Cancer Research Center, Seattle

Unknown

Asan Medical Center, Seoul

Samsung Medical Center, Seoul

Seoul National University Hospital, Seoul

Seoul Saint Mary's Hospital, Seoul

Severance Hospital, Seoul

03010

Hospital General Universitario de Alicante, Alicante

Sponsors

Lead Sponsor

All Listed Sponsors
lead

ALX Oncology Inc.

INDUSTRY