A Study to Investigate the Effect of CYP3A4 Inhibition on the Single Dose Pharmacokinetics of ASTX660 and the Effect of a Single Dose of ASTX660 on the Pharmacokinetics of the CYP3A4 Substrate Midazolam

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

May 20, 2020

Primary Completion Date

August 23, 2020

Study Completion Date

August 29, 2020

Conditions

Healthy Volunteer

Interventions

DRUG

ASTX660

Form: capsule; Route of administration: oral

DRUG

Midazolam

Form: syrup; Route of administration: oral

DRUG

Itraconazole

Form: capsule; Route of administration: oral

Trial Locations (1)

QPS Bio-kinetic, Springfield