25
Participants
Start Date
June 15, 2020
Primary Completion Date
December 31, 2021
Study Completion Date
July 31, 2022
Symptomatic drugs
indomethacin suppository 50-100 mg or an oral triptan, on maximum 3 days/10 days, only in case of very severe headache- and to use metoclopramide
Bridge therapy
prednisone 25 mg , 2 tablets after breakfast for 5 days, one tablet for 3 days, half tablet for 2 days ; bromazepam 1.5 mg, 1 tablet after breakfast, lunch and dinner for every day; pantoprazole 40 mg, 1 tablet after dinner every day
Mindfulness program
home based withdrawal program
Fondazione IRCCS Istituto Neurologico C. Besta, Neuroalgology Unit, Milan
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
OTHER