440
Participants
Start Date
July 8, 2021
Primary Completion Date
September 30, 2025
Study Completion Date
September 30, 2026
Intervention group_MRA
"Tidal Volume (Vt) =6-8 mL/kg of predicted body weight (PBW), Peep=8 cmH2O, recruitment maneuvers=30cm H2O every 30 min after intubation (except during CPB), after any disconnection and at the admission in ICU.~Recruitment maneuvers are performed in accordance with the surgical team an if SAP≥90 mmHg or MAP≥65 mmHg.~Ventilation is maintained during CPB Vt=2.5 mL/kg, Peep= 5 cmH2O"
Control group
Vt=6-8 mL/kg of PBW, Peep=5 cmH2O , No recruitment maneuvers. Ventilation maintained during CPB Vt=2.5 mL/kg, Peep= 5 cmH2O.
CHU Amiens-Picardie, Amiens
CHRU Brest, Brest
CHU de Dijon, Dijon
CHU de Nancy, Nancy
CHU Poitiers, Poitiers
CHU Rennes, Rennes
CHU de Rouen, Rouen
CHU Nantes, Saint-Herblain
CHU de Toulouse, Toulouse
CHRU Tours, Tours
Rennes University Hospital
OTHER