Nitrites, Skeletal Muscle Mitochondrial Bioenergetics, and Physical Activity in Old Age

PHASE2CompletedINTERVENTIONAL
Enrollment

64

Participants

Timeline

Start Date

April 23, 2021

Primary Completion Date

July 14, 2023

Study Completion Date

July 14, 2023

Conditions
AgingSedentary LifestyleFrailty
Interventions
DRUG

Placebos

Oral placebo capsule at a dose of 20 mg administered three times per day, during the day.

DRUG

20mg sodium nitrite tid

Oral, inorganic sodium nitrite capsule at a dose of 20 mg administered three times per day, during the day.

Trial Locations (1)

15213

University Of Pittsburgh, Pittsburgh

All Listed Sponsors
collaborator

National Institutes of Health (NIH)

NIH

collaborator

National Institute on Aging (NIA)

NIH

lead

Gladwin, Mark, MD

INDIV