The Role of Anti-inflammatory Cytokines and Antimicrobial Peptide LL-37 Biomarkers in the Treatment of Periodontal Disease.

CompletedOBSERVATIONAL
Enrollment

60

Participants

Timeline

Start Date

May 17, 2021

Primary Completion Date

June 30, 2022

Study Completion Date

July 15, 2022

Conditions
Periodontal DiseasesPeriodontitis
Interventions
DIAGNOSTIC_TEST

Crevicular fluid analysis by using ELISA testing.

Samples of crevicular fluid (fluid existing in the space between the gums and the roots of the teeth) will be obtained from healthy and periodontal patients. In periodontal patients, samples will be taken before and after receiving a routine course of periodontal treatment (root scale and polish) to assess the levels of a peptide called LL-37 and inflammatory cytokines (IL-4, IL-6, IL-10): Samples will then be analysed using laboratory procedures (ELISA)

Trial Locations (1)

28923

Clinica Universitaria Universidad Rey Juan Carlos, Alcorcón

All Listed Sponsors
lead

Universidad Rey Juan Carlos

OTHER