Non Invasive and Invasive Ventilation Post Extubation

CompletedOBSERVATIONAL
Enrollment

300

Participants

Timeline

Start Date

April 10, 2019

Primary Completion Date

April 2, 2020

Study Completion Date

April 20, 2020

Conditions
Respiratory Failure With Hypoxia
Interventions
DRUG

Midazolam

reconnected to mechanical ventilation before extubation for one hour with sedation with midazolam 3-5 milligram/hour intravenous infusion to achieve score 0 or -1on Richmond Agitation - Sedation Scale (RASS). 20 minutes before the end of this hour midazolam infusion discontinued and patients awaked. Patient put on mechanical ventilation (MV) with the following parameters, FIO2 40%, pressure SIMV mode, PEEP 8 cmH2O, Pressure support 15 cmH2O, Respiratory rate 14/min, Peak inspiratory pressure (PIP) of 35 cmH2O. Then patients extubated and followed our previous protocol without the use

DEVICE

ventilator

reconnected to mechanical ventilation before extubation for one hour with sedation

Trial Locations (1)

21944

King abd el Aziz specialist hospital, Ta'if

All Listed Sponsors
lead

King Abdul Aziz Specialist Hospital

NETWORK

NCT04402320 - Non Invasive and Invasive Ventilation Post Extubation | Biotech Hunter | Biotech Hunter